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人気の脳サプリメント、男性の寿命短縮に関連と研究者が指摘 – 毎日数百万が摂取中

iLIFE by iLIFE
2026年2月28日
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人気の脳サプリメント、男性の寿命短縮に関連と研究者が指摘 – 毎日数百万が摂取中
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**ニュース速報:グリシンの高濃度が男性の寿命短縮と関連**

2025年に発表された大規模な研究によると、脳機能向上や睡眠改善のサプリメントとして広く販売されているアミノ酸「グリシン」の高濃度が、男性の寿命を著しく短縮することが明らかになりました。この研究は、複数のコホートから20,000人以上の参加者のデータを分析したもので、血中のグリシン濃度が高い男性は、全死因死亡リスクが有意に高いことが分かりました。一方、女性にはそのような関連性は見られませんでした。

グリシンは、認知機能の向上、睡眠の質の改善、コラーゲン生成、さらには抗老化効果があるとして、最も一般的に購入されるアミノ酸サプリメントの一つです。推定によれば、数百万のアメリカ人が毎日摂取しており、しばしば他のノートロピックと組み合わせて朝のルーチンに取り入れています。オースティンに住む51歳のソフトウェアエンジニア、グレッグさんは、長寿フォーラムでの睡眠効果に関する情報を読んでから、毎晩3グラムのグリシンを4年間摂取していると語りました。「誰も欠点については言わなかった」と彼は言います。

研究者たちは、グリシンが体内で二重の役割を果たすことを指摘しました。神経伝達物質およびタンパク質の構造成分として機能する一方で、血中濃度の上昇は、男性における基礎的な代謝機能障害と相関しているようです。具体的には、肝臓のストレスやミトコンドリア機能の障害を示すマーカーが含まれます。この性別特有の発見は、研究者たちをも驚かせました。一つの仮説として、ホルモンプロファイルに影響されるアミノ酸の代謝の違いが、男性をグリシンの蓄積に対してより脆弱にしている可能性が考えられています。

研究者たちは、グリシンのレベルが既存の健康問題のバイオマーカーとして機能する可能性があると強調しましたが、死亡率との相関はすべてのコホートで堅固でした。この発見は、男性がグリシンを慢性的に補充することが、代謝の警告サインを見逃している可能性があることを示唆しており、サプリメントの最適化よりも血液検査の重要性が高いことを示しています。

詳細については、DMNewsをGoogleニュースフィードに追加してください。

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