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    Ronnie Coleman Signature Series XS Series standalone NAC

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    Newtrend Group Invests RMB20.5 Million in Equipment for New Glycine Base

    Reversal of protein chemical aging by enzymatic deglycation

    Reversal of protein chemical aging by enzymatic deglycation

    Researchers froze the simplest amino acid to nearly minus 260°C and bombarded it with radiation that mimics cosmic rays — and it formed peptides, the building blocks of proteins, under conditions that exist before stars and planets are born

    Researchers froze the simplest amino acid to nearly minus 260°C and bombarded it with radiation that mimics cosmic rays — and it formed peptides, the building blocks of proteins, under conditions that exist before stars and planets are born

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    Frishantic Launches Chelated Magnesium Glycinate for Nighttime Calm and Daily Muscle Ease

    Newtrend Group Invests RMB20.5 Million in Equipment for New Glycine Base

    Newtrend Group Invests RMB20.5 Million in Equipment for New Glycine Base

    Reversal of protein chemical aging by enzymatic deglycation

    Reversal of protein chemical aging by enzymatic deglycation

    Researchers froze the simplest amino acid to nearly minus 260°C and bombarded it with radiation that mimics cosmic rays — and it formed peptides, the building blocks of proteins, under conditions that exist before stars and planets are born

    Researchers froze the simplest amino acid to nearly minus 260°C and bombarded it with radiation that mimics cosmic rays — and it formed peptides, the building blocks of proteins, under conditions that exist before stars and planets are born

    Controlling glycine polymorphs through nanoconfinement

    Controlling glycine polymorphs through nanoconfinement

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銅パラドデカツングステート-B化合物の合成、構造、抗がん活性:グリシン配位子による装飾

iLIFE by iLIFE
2025年4月22日
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この研究では、ポリオキソメタレートに基づく無機-有機ハイブリッド材料、Na4[Cu4(Gly)2(HGly)2(H4W12O42)]Cl2·20H2O(1)(Gly = グリシン)が、自己集合アプローチを用いて合成されました。この過程で、銅イオンとグリシンがパラドデカトンスタートアニオン[H4W12O42]8–に組み込まれました。化合物1の構造と特性は、単結晶X線回折、元素分析、粉末X線回折、FTIR、ラマン分光法、サイクリックボルタンメトリー(CV)、およびUV-Vis分光法を用いて系統的に特定されました。さらに、その抗がん活性は、MTTアッセイを用いてヒト肝癌細胞(HepG2)およびヒト腎上皮細胞(HEK293T)に対してin vitroで評価され、IC50値は36.232 ± 0.41 μMとなりました。この結果は、化合物1が肝癌細胞の増殖を効果的に抑制することを示しており、ポリオキソトンスタート(POT)に基づく抗がん薬の開発候補としての可能性を強調しています。

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